Facile one-pot synthesis of 5-substituted hydantoins

Org Biomol Chem. 2008 Mar 21;6(6):988-91. doi: 10.1039/b719675j. Epub 2008 Feb 14.

Abstract

5-Substituted and 5,5-disubstituted hydantoins are synthesised from the corresponding aldehydes or ketones, using a one-pot, gallium(III) triflate-catalysed procedure that is compatible with a range of substrates and solvents.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Catalysis
  • Hydantoins / chemical synthesis*
  • Hydantoins / chemistry
  • Ketones / chemistry
  • Mesylates / chemistry
  • Molecular Structure

Substances

  • Aldehydes
  • Hydantoins
  • Ketones
  • Mesylates
  • gallium triflate