Abstract
This observational study was conducted in 235 patients undergoing IVF who had a cervical swab positive for Chlamydia trachomatis and who underwent antibiotic treatment until a negative cervical swab before IVF attempt. After oocyte retrieval, follicular fluids of 109 patients out of 228 still showed the presence of IgA antichlamydia antibodies and a significantly lower pregnancy and implantation rate; therefore we conclude that patients should undergo IVF procedure after serum antichlamydia IgA tests negative.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Antibodies, Bacterial / metabolism
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Autoimmunity*
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Cervix Uteri / microbiology*
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Chlamydia Infections / drug therapy
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Chlamydia Infections / immunology
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Chlamydia Infections / microbiology*
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Chlamydia trachomatis / immunology
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Chlamydia trachomatis / isolation & purification*
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Embryo Implantation*
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Female
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Fertilization in Vitro*
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Follicular Fluid / immunology
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Follicular Fluid / microbiology
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Humans
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Immunoglobulin A / blood
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Italy
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Oocyte Retrieval
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Pregnancy
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Pregnancy Rate*
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Time Factors
Substances
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Anti-Bacterial Agents
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Antibodies, Bacterial
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Immunoglobulin A