Abstract
A 72 year-old man. He was diagnosed with rheumatoid arthritis in 2002. In January 2005 he noted productive cough and fever; he was diagnosed as eosinophilic pneumonia (EP). We discontinued administration of bucillamine and methotrexate and started to treat with oral prednisolone 30 mg daily. To rule out drug-induced EP, prednisolone was tapered by 10 mg per week. Consolidation occurred in the right lower lobe when prednisolone was decreased to 5 mg daily. After increasing the dose of prednisolone to 30 mg daily again, consolidation was promptly resolved. It was considered to be important to rule out drug-induced EP.
MeSH terms
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Aged
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Antirheumatic Agents / therapeutic use
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Arthritis, Rheumatoid / complications*
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Arthritis, Rheumatoid / drug therapy
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Cysteine / analogs & derivatives
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Cysteine / therapeutic use
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Diagnosis, Differential
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Glucocorticoids / adverse effects
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Glucocorticoids / therapeutic use
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Humans
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Male
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Methotrexate / therapeutic use
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Prednisolone / adverse effects
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Prednisolone / therapeutic use
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Pulmonary Eosinophilia / chemically induced
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Pulmonary Eosinophilia / diagnosis*
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Pulmonary Eosinophilia / etiology*
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Antirheumatic Agents
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Glucocorticoids
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Prednisolone
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Cysteine
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bucillamine
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Methotrexate