Lung transplantation in a patient with a thrombophilic disorder

O Elidemir; K J Smith; M G Schecter; H Seethamraju; D H Mahoney; E D McKenzie; G B Mallory

doi:10.1111/j.1399-3046.2007.00815.x

Lung transplantation in a patient with a thrombophilic disorder

Pediatr Transplant. 2008 May;12(3):368-71. doi: 10.1111/j.1399-3046.2007.00815.x. Epub 2008 Mar 12.

Authors

O Elidemir¹, K J Smith, M G Schecter, H Seethamraju, D H Mahoney, E D McKenzie, G B Mallory

Affiliation

¹ Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. [email protected]

PMID: 18346036
DOI: 10.1111/j.1399-3046.2007.00815.x

Abstract

The prothrombin G20210A mutation has been associated with an increased risk of graft failure in renal transplant recipients. Little is known about the potential effect of this mutation on lung transplant recipients. We report the case of bilateral lung transplantation in a patient with cystic fibrosis who was heterozygous for the G20210A mutation of the prothrombin gene.

Publication types

Case Reports

MeSH terms

Adult
Cystic Fibrosis / complications
Cystic Fibrosis / genetics*
Cystic Fibrosis / surgery
Cystic Fibrosis / therapy*
Enoxaparin / therapeutic use
Fatal Outcome
Female
Heparin / therapeutic use
Heterozygote
Humans
Hypertension, Pulmonary / etiology
Lung Transplantation / methods*
Mental Disorders / complications
Mutation*
Prothrombin / genetics*
Risk
Thrombophilia / complications*
Thrombophilia / genetics

Substances

Enoxaparin
Prothrombin
Heparin