Abstract
In this commentary we stress that serum bactericidal activity is now internationally accepted as correlate of protection for evaluating new vaccines for epidemic and endemic meningococcal B control, and that the standardization of the assay and the choice of representative strains for each of the vaccine candidates are critical.
MeSH terms
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Antibodies, Bacterial / biosynthesis*
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Antigens, Bacterial / immunology
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Blood Bactericidal Activity*
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Clinical Trials as Topic
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Drug Design*
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Humans
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Meningococcal Infections / prevention & control*
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Meningococcal Vaccines / administration & dosage
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Meningococcal Vaccines / immunology*
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Meningococcal Vaccines / therapeutic use
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Neisseria meningitidis, Serogroup B / immunology*
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Porins / immunology
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Recombinant Proteins / immunology
Substances
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Antibodies, Bacterial
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Antigens, Bacterial
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Meningococcal Vaccines
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Porins
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Recombinant Proteins
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porin protein, Neisseria