Abstract
A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient's B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Anthrax / epidemiology*
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Anthrax / microbiology
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Antigens, Bacterial / genetics
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Bacillus anthracis / classification*
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Bacillus anthracis / genetics*
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Bacterial Proteins / genetics
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Bacterial Toxins / genetics
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DNA, Bacterial / chemistry
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Genotype
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Humans
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Inhalation Exposure
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Phylogeny
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Polymorphism, Single Nucleotide*
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Russia / epidemiology
Substances
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Antigens, Bacterial
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Bacterial Proteins
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Bacterial Toxins
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DNA, Bacterial
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anthrax toxin