Abstract
In a randomised second look laparoscopic study, concomitant antibiotic--anti-inflammatory therapy for the treatment of pelvic inflammatory disease (P.I.D.) was studied. Six weeks after medical treatment results were evaluated during second look laparoscopy based on three parameters: residual inflammation, pelvic adhesions and tubal patency. The combination treatment resulted in decreased pelvic adhesion and tubal occlusion in severe forms of P.I.D. Anti-inflammatory agents combined with anti-biotics are not more beneficial than anti-biotics alone in mild and moderate forms of P.I.D. so combination therapy must be reserved for severe forms of P.I.D.
Publication types
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Clinical Trial
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English Abstract
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Randomized Controlled Trial
MeSH terms
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Administration, Oral
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Adult
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Amoxicillin / administration & dosage
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Amoxicillin / therapeutic use*
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Amoxicillin-Potassium Clavulanate Combination
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Clavulanic Acids / administration & dosage
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Clavulanic Acids / therapeutic use*
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Doxycycline / administration & dosage
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Doxycycline / therapeutic use*
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Drug Therapy, Combination / administration & dosage
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Drug Therapy, Combination / therapeutic use
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Female
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Humans
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Infusions, Intravenous
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Laparoscopy
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Piroxicam / administration & dosage
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Piroxicam / therapeutic use*
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Pregnancy
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Pregnancy Outcome
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Prognosis
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Salpingitis / diagnosis
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Salpingitis / drug therapy*
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Salpingitis / pathology
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Severity of Illness Index
Substances
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Clavulanic Acids
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Piroxicam
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Amoxicillin-Potassium Clavulanate Combination
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Amoxicillin
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Doxycycline