DNA-templated CMV viral capsid proteins assemble into nanotubes

Chem Commun (Camb). 2008 Jan 7:(1):49-51. doi: 10.1039/b715299j.

Abstract

This communication describes the in vitro assembly of genetically recombinant Cucumber Mosaic Virus (CMV) viral capsid proteins (CPs) into biological nanotubes, several micrometres long yet with a diameter of only approximately 17 nm, triggered by double-stranded DNAs of different lengths.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Capsid Proteins / chemistry*
  • Capsid Proteins / genetics*
  • Capsid Proteins / ultrastructure
  • Circular Dichroism
  • Cucumovirus / chemistry*
  • Cucumovirus / genetics
  • Cucumovirus / ultrastructure
  • DNA / genetics*
  • Microscopy, Electron, Transmission
  • Nanotubes / chemistry*
  • Nanotubes / ultrastructure
  • Templates, Genetic

Substances

  • Capsid Proteins
  • DNA