Massive upper gastrointestinal bleeding from pure metastatic choriocarcinoma in patient with mixed germ cell tumor with subclinical intestinal metastasis

Urology. 2009 Feb;73(2):443.e15-7. doi: 10.1016/j.urology.2008.02.044. Epub 2008 Apr 14.

Abstract

Although testicular germ cell tumors have become curable neoplasms, a better understanding of the clinicopathologic features is needed for the rare manifestations associated with treatment failure. We report a rare case of metastatic pure choriocarcinoma involving the small intestine arising from a testicular mixed germ cell tumor. In a patient who developed massive upper gastrointestinal hemorrhage during treatment, the intestinal metastases and focus of bleeding could only be determined by laparotomy. We propose an approach for the determination of subclinical intestinal metastases of testicular germ cell tumor; the case is discussed in light of similar reports in literature.

Publication types

  • Case Reports

MeSH terms

  • Choriocarcinoma / complications*
  • Choriocarcinoma / secondary*
  • Gastrointestinal Hemorrhage / etiology*
  • Humans
  • Ileal Neoplasms / complications*
  • Ileal Neoplasms / secondary*
  • Jejunal Neoplasms / complications*
  • Jejunal Neoplasms / secondary*
  • Male
  • Neoplasms, Germ Cell and Embryonal / complications*
  • Neoplasms, Germ Cell and Embryonal / secondary*
  • Neoplasms, Multiple Primary / complications*
  • Testicular Neoplasms / complications*
  • Testicular Neoplasms / pathology*
  • Young Adult