Abstract
Scintillation proximity assay technologies provide a rapid non-separation method to measure common biological interactions using radioactively tagged molecules. This unit identifies potential uses of the technology for the measurement of receptor-ligand binding, cAMP accumulation, GTP binding to heterotrimeric G proteins, protease activity and cellular uptake.
MeSH terms
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Animals
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Biological Assay / methods*
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Cyclic AMP / metabolism
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Dose-Response Relationship, Drug
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GTP-Binding Proteins / metabolism
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Protein Binding / drug effects
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Radioligand Assay*
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Receptors, Serotonin / metabolism
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Scintillation Counting / methods*
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Serotonin / pharmacokinetics
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Serotonin Agents / pharmacology
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Time Factors
Substances
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Receptors, Serotonin
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Serotonin Agents
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serotonin 1E receptor
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Serotonin
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Cyclic AMP
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GTP-Binding Proteins