Living donor liver transplantation in polycystic liver disease

Liver Transpl. 2008 May;14(5):680-3. doi: 10.1002/lt.21423.

Abstract

In the current Model for End-Stage Liver Disease system, patients with polycystic liver disease (PCLD) who have a poor quality of life secondary to their massive hepatomegaly are no longer competitive for a deceased donor liver transplant if their liver function is well preserved. Traditionally, a caval resection has been advocated in these patients because of the difficulty of the hepatectomy with hepatomegaly, which makes living donation impossible. This series looks at 3 patients who underwent a caval sparing hepatectomy and subsequent living donor liver transplantation (LDLT) for PCLD. Graft and patient survival was 100%, and there were few complications in either donors or recipients. LDLT is an ideal option for patients with PCLD and preserved liver function but poor quality of life.

MeSH terms

  • Adult
  • Cysts / complications
  • Cysts / mortality
  • Cysts / physiopathology
  • Cysts / surgery*
  • Female
  • Graft Survival*
  • Hepatectomy
  • Hepatomegaly / etiology
  • Hepatomegaly / surgery
  • Humans
  • Liver Diseases / complications
  • Liver Diseases / mortality
  • Liver Diseases / physiopathology
  • Liver Diseases / surgery*
  • Liver Function Tests
  • Liver Transplantation*
  • Living Donors*
  • Middle Aged
  • Patient Selection
  • Quality of Life
  • Retrospective Studies
  • Treatment Outcome