[Chronic parkinsonian syndrome after 10 years of repeated insecticide spraying]

Rev Neurol (Paris). 2008 Apr;164(4):374-6. doi: 10.1016/j.neurol.2007.08.011. Epub 2008 Feb 1.
[Article in French]

Abstract

Introduction: Acute and reversible parkinsonism is usually described after massive ingestion of organophosphate insecticides whereas acute intoxications occurring after pesticide spraying are rare.

Case report: We report one case of atypical parkinsonian disorder following repeated spraying with an aerosol insecticide containing pyrethre and organophosphate. This patient had a daily massive dermal and respiratory exposure to these pesticides for 10 years. Cerebral MRI was normal. DAT-scan showed a presynaptic loss of function.

Conclusion: Pesticides are suspected to be one risk factor responsible for parkinsonism. The present case supports this environmental hypothesis.

Publication types

  • Case Reports

MeSH terms

  • Agricultural Workers' Diseases / diagnostic imaging
  • Agricultural Workers' Diseases / pathology*
  • Brain / diagnostic imaging
  • Brain / pathology
  • Chronic Disease
  • Humans
  • Insecticides / adverse effects*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Organophosphorus Compounds / adverse effects
  • Parkinsonian Disorders / chemically induced*
  • Parkinsonian Disorders / diagnostic imaging
  • Parkinsonian Disorders / psychology
  • Pyrethrins / adverse effects
  • Radionuclide Imaging

Substances

  • Insecticides
  • Organophosphorus Compounds
  • Pyrethrins