Abstract
An association between anti-phospholipid antibodies and different disorders of the central nervous system has been described recently. We used an ELISA technique and detected anti-cardiolipin antibodies of the IgG or IgM variety in a series of 10 patients: 4 had occlusive stroke, 2 brain hemorrhage, 2 chorea, 1 a Sneddon syndrome and 1 vascular cephalea. The diagnosis of primary anti-phospholipid syndrome was suggested after ruling out systemic lupus in all patients.
Publication types
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Case Reports
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Antibodies, Anticardiolipin / analysis*
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Antibodies, Anticardiolipin / metabolism
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Antiphospholipid Syndrome / complications*
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Antiphospholipid Syndrome / diagnosis
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Antiphospholipid Syndrome / immunology
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Cerebral Infarction / complications*
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Cerebral Infarction / diagnosis
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Cerebral Infarction / immunology
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Enzyme-Linked Immunosorbent Assay
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Female
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Humans
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Immunoglobulin G / blood
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Immunoglobulin M / blood
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Male
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Middle Aged
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Risk Factors
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Tomography, X-Ray Computed
Substances
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Antibodies, Anticardiolipin
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Immunoglobulin G
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Immunoglobulin M