Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells

Leuk Lymphoma. 2008 Jun;49(6):1206-8. doi: 10.1080/10428190801993496.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antigens, CD34 / immunology
  • Antigens, CD34 / metabolism*
  • Cells, Cultured
  • Colony-Forming Units Assay
  • Fetal Blood / cytology
  • Fetal Blood / metabolism
  • Granulocyte-Macrophage Colony-Stimulating Factor / pharmacology*
  • Green Fluorescent Proteins / genetics
  • Green Fluorescent Proteins / metabolism
  • Hematopoietic Stem Cells / physiology*
  • Humans
  • Mice
  • Mitogen-Activated Protein Kinases / metabolism
  • NIH 3T3 Cells
  • Phosphatidylinositol 3-Kinases / metabolism*
  • Phosphorylation
  • Protein Subunits

Substances

  • Antigens, CD34
  • Protein Subunits
  • enhanced green fluorescent protein
  • Green Fluorescent Proteins
  • Granulocyte-Macrophage Colony-Stimulating Factor
  • Phosphatidylinositol 3-Kinases
  • Mitogen-Activated Protein Kinases