Lung transplantation and lung volume reduction surgery versus transplantation in chronic obstructive pulmonary disease

Proc Am Thorac Soc. 2008 May 1;5(4):447-53. doi: 10.1513/pats.200707-107ET.

Abstract

Lung transplantation and lung volume reduction surgery are surgical options for patients with advanced chronic obstructive pulmonary disease that is refractory to medical treatment. In this review, we discuss the differential indications for each procedure, as well as compare their risks and benefits. We also present an algorithm for selecting the most appropriate procedure for individual patients. Finally, we discuss the feasibility and role of lung transplantation after lung volume reduction surgery in the management of selected patients with chronic obstructive pulmonary disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cost-Benefit Analysis
  • Decision Making
  • Exercise Tolerance
  • Humans
  • Lung Transplantation* / mortality
  • Patient Selection
  • Pneumonectomy / methods*
  • Pneumonectomy / mortality
  • Postoperative Complications
  • Pulmonary Disease, Chronic Obstructive / mortality
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / surgery*
  • Quality of Life
  • Respiratory Function Tests
  • Respiratory Muscles / physiology
  • Risk Factors
  • Survival Analysis