One new triterpenoid from biotransformation product of glycyrrhizic acid

J Asian Nat Prod Res. 2008 May-Jun;10(5-6):463-6. doi: 10.1080/10286020801948250.

Abstract

A new triterpenoid compound (1) and a known compound (2) were isolated from the product of biotransformation of glycyrrhizic acid by Aspergillus niger. On the basis of the 1D and 2D NMR ((1)H-(1)H COSY, HSQC, HMBC and NOESY) and MS spectrometry, their structures were established as 7beta, 15alpha-dihydroxy-3,11-dioxo-oleana-12-en-30-oic acid (1) and 15alpha-hydroxy-3,11-dione-oleana-12-en-30-oic acid (2), respectively.

MeSH terms

  • Aspergillus niger / metabolism
  • Biotransformation
  • Glycyrrhiza / chemistry
  • Glycyrrhizic Acid / analogs & derivatives*
  • Glycyrrhizic Acid / metabolism
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • Triterpenes
  • Glycyrrhizic Acid