NMR-guided fragment-based approach for the design of AAC(6')-Ib ligands

Chembiochem. 2008 Jun 16;9(9):1368-71. doi: 10.1002/cbic.200700677.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetyltransferases / antagonists & inhibitors*
  • Acetyltransferases / metabolism*
  • Aminoglycosides / metabolism
  • Binding Sites
  • Drug Design*
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / metabolism*
  • Enzyme Inhibitors / pharmacology
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Protein Binding

Substances

  • Aminoglycosides
  • Enzyme Inhibitors
  • Ligands
  • Acetyltransferases
  • aminoglycoside N(6')-acetyltransferase