What are the consequences of phosphorylation and hyperphosphorylation of ryanodine receptors in normal and failing heart?

Circ Res. 2008 May 9;102(9):995-7. doi: 10.1161/CIRCRESAHA.108.176172.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adrenergic beta-Agonists / pharmacology
  • Animals
  • Calcium / metabolism*
  • Calcium Signaling* / drug effects
  • Cyclic AMP-Dependent Protein Kinases / metabolism
  • Heart Failure / metabolism*
  • Heart Failure / physiopathology
  • Humans
  • Mice
  • Mice, Transgenic
  • Myocardial Contraction* / drug effects
  • Myocardium / enzymology
  • Myocardium / metabolism*
  • Phosphorylation
  • Ryanodine Receptor Calcium Release Channel / genetics
  • Ryanodine Receptor Calcium Release Channel / metabolism*
  • Serine / metabolism

Substances

  • Adrenergic beta-Agonists
  • Ryanodine Receptor Calcium Release Channel
  • Serine
  • Cyclic AMP-Dependent Protein Kinases
  • Calcium