Abstract
To evaluate nosocomial infections due to imipenem-resistant and imipenem-susceptible Pseudomonas aeruginosa, a case-control study that included genotyping was performed. Hospitalization for more than 15 days was independently associated with infection with an imipenem-resistant organism. Sixty-seven percent of the imipenem-resistant isolates analyzed and 23% of the imipenem-susceptible isolates analyzed belonged to a single clone. Intervention led to a decrease in the number of infections due to imipenem-resistant and imipenem-susceptible P. aeruginosa.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Case-Control Studies
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Cross Infection / epidemiology
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Cross Infection / microbiology
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Cross Infection / prevention & control*
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Drug Resistance, Bacterial / genetics*
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Female
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Genotype
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Humans
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Imipenem / pharmacology
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Infection Control / methods
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Length of Stay
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Male
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Middle Aged
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Pseudomonas Infections / epidemiology
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Pseudomonas Infections / microbiology
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Pseudomonas Infections / prevention & control*
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Pseudomonas aeruginosa / classification
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Pseudomonas aeruginosa / drug effects*
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Pseudomonas aeruginosa / genetics
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Risk Factors
Substances
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Anti-Bacterial Agents
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Imipenem