Dehydrophenylalanine (DeltaPhe) as a beta breaker: extended structure terminated by a DeltaPhe-induced turn in the pentapeptide Boc-Phe1-Ala2-Ile3-DeltaPhe4-Ala5-OMe

Chembiochem. 2008 Jun 16;9(9):1375-8. doi: 10.1002/cbic.200800053.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Amyloid beta-Peptides / chemistry
  • Amyloid beta-Peptides / metabolism
  • Circular Dichroism
  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Oligopeptides / chemical synthesis
  • Oligopeptides / chemistry*
  • Phenylalanine / analogs & derivatives*
  • Phenylalanine / chemistry
  • Phenylalanine / pharmacology
  • Protein Structure, Secondary / drug effects*

Substances

  • Amyloid beta-Peptides
  • Oligopeptides
  • Phenylalanine
  • phenyldehydroalanine