Abstract
The three new pentacyclic triterpenes 1-3 were isolated and elucidated from the roots of Gypsophila oldhamiana, together with seven known triterpenes (4-10). These triterpenes were evaluated for their glycogen phosphorylase inhibitory activity and preliminary structure-activity trends are suggested.
MeSH terms
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Caryophyllaceae / chemistry*
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Enzyme Inhibitors / chemistry*
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Enzyme Inhibitors / pharmacology*
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Glycogen Phosphorylase / antagonists & inhibitors*
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Glycogen Phosphorylase / metabolism
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Pentacyclic Triterpenes / chemistry*
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Pentacyclic Triterpenes / pharmacology*
Substances
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Enzyme Inhibitors
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Pentacyclic Triterpenes
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Glycogen Phosphorylase