B cell depletion and a T cell-targeted therapy allows to control the sudden onset of diabetes and lupus, without steroids

MeSH terms

• Adult
• Antibodies, Monoclonal / therapeutic use
• Antibodies, Monoclonal, Murine-Derived
• Antirheumatic Agents / therapeutic use
• B-Lymphocytes / pathology*
• Combined Modality Therapy
• Cyclosporine / therapeutic use
• Diabetes Mellitus, Type 1 / complications
• Diabetes Mellitus, Type 1 / immunology
• Diabetes Mellitus, Type 1 / therapy*
• Drug Delivery Systems
• Female
• Humans
• Immunosuppression Therapy / methods
• Immunosuppressive Agents / therapeutic use
• Leukapheresis* / methods
• Lupus Erythematosus, Systemic / complications
• Lupus Erythematosus, Systemic / immunology
• Lupus Erythematosus, Systemic / therapy*
• Rituximab
• T-Lymphocytes / drug effects*
• T-Lymphocytes / immunology
• T-Lymphocytes / pathology
• Treatment Outcome