Folding of long-chain alkanediammonium ions promoted by a cucurbituril derivative

Wei-Hao Huang; Peter Y Zavalij; Lyle Isaacs

doi:10.1021/ol800893n

Folding of long-chain alkanediammonium ions promoted by a cucurbituril derivative

Org Lett. 2008 Jun 19;10(12):2577-80. doi: 10.1021/ol800893n. Epub 2008 May 27.

Authors

Wei-Hao Huang¹, Peter Y Zavalij, Lyle Isaacs

Affiliation

¹ Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.

PMID: 18503277
DOI: 10.1021/ol800893n

Abstract

We report the isolation and characterization of two top-bottom differentiated CB[n]-type receptors, namely ns-CB[6] and cucurbituril derivative 2, which display diastereoselective recognition toward unsymmetrical guests. Compound 2 also promotes the back-folding of long chain alkanediammonium ions in water.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Crystallography, X-Ray
Macrocyclic Compounds / chemistry*
Models, Molecular
Molecular Conformation
Molecular Structure
Quaternary Ammonium Compounds / chemistry*
Stereoisomerism
Water

Substances

Macrocyclic Compounds
Quaternary Ammonium Compounds
cucurbit(n)uril
Water