Neuropsychiatric symptoms and quality of life in patients in the final phase of dementia

Int J Geriatr Psychiatry. 2009 Jan;24(1):25-32. doi: 10.1002/gps.2040.

Abstract

Objectives: To assess neuropsychiatric symptoms and quality of life in a group of patients in the final phase of dementia.

Methods: All patients with dementia (n = 216) residing on dementia special care units of two Dutch nursing homes were included in the study provided they met the criteria for the final phase of dementia. Neuropsychiatric symptoms were assessed with the Neuropsychiatric Inventory Nursing Home version (NPI-NH) and the Cohen Mansfield Agitation Inventory (CMAI). Quality of life was assessed with the QUALIDEM.

Results: Of the 216 dementia patients 39 met the criteria for the final phase of dementia. The patients showed a specific pattern of behaviours with a high prevalence of apathy, agitation and behaviours that were mainly observed during morning care such as making strange noises, grabbing, performing repetitious mannerism, spitting, hitting, screaming and pushing. Overall quality of life of these patients in the final phase of dementia was moderate.

Conclusion: In this small sample, patients in the final phase of dementia show specific behavioural problems, that mainly should be addressed with psychosocial interventions.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antipsychotic Agents / therapeutic use
  • Dementia / drug therapy
  • Dementia / psychology*
  • Female
  • Homes for the Aged
  • Humans
  • Male
  • Mental Disorders / drug therapy
  • Mental Disorders / psychology
  • Nursing Homes
  • Psychiatric Status Rating Scales
  • Quality of Life*

Substances

  • Antipsychotic Agents