Neuropathy following acute intoxication with Mecarbam (OP ester)

Acta Neurol Scand. 1991 Mar;83(3):198-200. doi: 10.1111/j.1600-0404.1991.tb04677.x.

Abstract

Only a small number of organophosphorous compounds, of the many thousands circulating on the market, has been reported as causing neuropathy with delayed onset. A case is presented of a young male who in an attempt to commit suicide by taking a massive dose of Mecarbam, developed polyneuropathy accompanied by a mild involvement of the CNS. Mecarbam is herewith reported for the first time as an agent which can affect the peripheral nervous system.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dose-Response Relationship, Drug
  • Electromyography / drug effects
  • Follow-Up Studies
  • Humans
  • Insecticides*
  • Male
  • Motor Neurons / drug effects
  • Neurologic Examination
  • Neuromuscular Diseases / chemically induced*
  • Neuromuscular Diseases / diagnosis
  • Organophosphate Poisoning*
  • Organothiophosphates
  • Reaction Time / drug effects
  • Suicide, Attempted*
  • Synaptic Transmission / drug effects

Substances

  • Insecticides
  • Organothiophosphates
  • mecarbam