Abstract
Four new abietane diterpenoids, fortunins A-D (1-4), and six new 18-hydroxymethylene abietane diterpenoids, fortunins E-J (5-10), along with 12 known diterpenoids, were isolated from the bark of Cryptomeria fortunei. The structures of new compounds were established on the basis of 1D and 2D NMR and other spectroscopic analyses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Abietanes / chemistry
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Abietanes / isolation & purification*
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Abietanes / pharmacology
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Cryptomeria / chemistry*
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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HL-60 Cells
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Humans
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Molecular Structure
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Plant Bark / chemistry
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Plants, Medicinal / chemistry*
Substances
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Abietanes
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Antineoplastic Agents, Phytogenic
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Drugs, Chinese Herbal