The incidence of perinatal problems in infants might be the one of the main reasons in delayed psychomotor development. The most predictive for future delay in psychomotor development are the pathology of pregnancy and delivery, an intra-uterine infection, incomplete pregnancy and the hypoxic--ischemic injury of the brain. Adequate conduct of the perinatal period, definition of existing or expected problems and preventive measures allows avoiding or reducing pathological conditions and possible future consequences. The goal of the investigation was to determine the structural features of perinatal risk factors contributing to the future delay in psychomotor development. 348 newborns during 24 months have been examined. It was concluded that perinatal risk factors contribute in the structure of future delay of psychomotor development significantly. Early revealing and adequate conducting of the perinatal period, definition of existing or expected problems and adequate measures allows to avoid or reduce possible pathological conditions, their complications and their consequences.