Voice, swallowing and quality of life in patients after transoral laser surgery for supraglottic carcinoma

J Surg Oncol. 2008 Sep 1;98(3):184-9. doi: 10.1002/jso.21101.

Abstract

Background: Transoral laser surgery is a conservative surgical method used to treat supraglottic carcinomas, but little is known about functional and quality of life (QOL) outcomes relative to extent of resection.

Methods: We prospectively examined functional and oncological outcomes of 21 patients with T1-T3 supraglottic carcinomas underwent partial (group A, n = 8) or radical (group B, n = 13) laser supraglottic resection and bilateral neck dissection. Subjective and objective evaluation of voice, swallowing and QOL before and after endoscopic supraglottic resection were compared between the two groups.

Results: No major complications were encountered, but local recurrence developed in two patients (9%). Vocal function was not generally affected by surgery. Postsurgical swallowing and social eating scores were higher in group B than in group A (P < 0.05). Aspiration occurred in most patients soon after surgery, but recovered within 3-6 months, with recovery being faster in group A. Three-year locoregional control, disease-free survival and overall survival rates were 81%, 71% and 79%, respectively.

Conclusion: Swallowing was affected by the extent of laser resection for supraglottic carcinomas, but eventually recovered in most patients, indicating favourable functional and oncological outcomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Cohort Studies
  • Deglutition / physiology*
  • Female
  • Follow-Up Studies
  • Glottis / pathology
  • Glottis / surgery*
  • Humans
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / surgery*
  • Laryngectomy
  • Laser Therapy / methods*
  • Male
  • Middle Aged
  • Oral Surgical Procedures / methods
  • Prospective Studies
  • Quality of Life*
  • Treatment Outcome
  • Voice / physiology*