Urease inhibitor from Datisca cannabina linn

J Enzyme Inhib Med Chem. 2008 Jun;23(3):386-90. doi: 10.1080/14756360701536513.

Abstract

A new flavonoid datisdirin (1), along with eight known compounds tectochrysine, cearoin, sideroxyline, ursolic acid, corosolic acid, arjunolic acid, erythrodiol and oleanolic acid, were isolated from the ethyl acetate fraction of D. cannabina Linn. The structure of compound 1 was deduced on the basis of its spectral data. Datisdirin showed activity against the ureases enzyme.

MeSH terms

  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / isolation & purification
  • Enzyme Inhibitors / pharmacology
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology
  • Molecular Structure
  • Plant Proteins / isolation & purification
  • Plant Proteins / pharmacology*
  • Urease / antagonists & inhibitors*

Substances

  • Enzyme Inhibitors
  • Flavonoids
  • Plant Proteins
  • Urease