Abstract
Purpose:
To describe the clinical course of a case of intravascular lymphoma.
Design:
Case report.
Methods:
Retrospective chart review.
Results:
A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints.
Conclusions:
Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.
MeSH terms
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Antibodies, Monoclonal / therapeutic use
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Antibodies, Monoclonal, Murine-Derived
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Biopsy
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Blood Vessels / pathology
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Cyclophosphamide / therapeutic use
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Diagnosis, Differential
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Doxorubicin / therapeutic use
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Fluorescein Angiography
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Humans
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L-Lactate Dehydrogenase / blood
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Lymphoma / complications
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Lymphoma / diagnosis*
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Lymphoma / drug therapy
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Lymphoma / enzymology
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Male
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Middle Aged
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Prednisolone / therapeutic use
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Rituximab
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Skin / pathology
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Treatment Outcome
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Uveomeningoencephalitic Syndrome / diagnosis*
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Vascular Neoplasms / complications
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Vascular Neoplasms / diagnosis*
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Vascular Neoplasms / drug therapy
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Vascular Neoplasms / enzymology
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Vincristine / therapeutic use
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Vision Disorders / etiology
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Murine-Derived
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Rituximab
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisolone
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L-Lactate Dehydrogenase