Case of acute generalized exanthematous pustulosis caused by ampicillin/cloxacillin sodium in a pregnant woman

J Dermatol. 2008 Jun;35(6):362-4. doi: 10.1111/j.1346-8138.2008.00484.x.

Abstract

We report a case of acute generalized exanthematous pustulosis (AGEP) induced by ampicillin/cloxacillin sodium (ABPC/MCIPC) in a pregnant woman. AGEP is caused mostly by drugs. Among them, beta-lactam antibiotics account for a high proportion of the cases, predominantly by amoxicillin. To our knowledge, this is only the second case ever reported in the Japanese language published work of AGEP induced by ABPC/MCIPC.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amoxicillin / administration & dosage
  • Amoxicillin / adverse effects*
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Cloxacillin / administration & dosage
  • Cloxacillin / adverse effects*
  • Drug Combinations
  • Drug Eruptions / etiology*
  • Drug Eruptions / pathology
  • Exanthema / etiology*
  • Exanthema / pathology
  • Female
  • Humans
  • Lymphocyte Activation / drug effects
  • Patch Tests
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy
  • Skin / pathology
  • Skin Diseases, Vesiculobullous / chemically induced*
  • Skin Diseases, Vesiculobullous / pathology
  • Streptococcal Infections / drug therapy

Substances

  • Anti-Bacterial Agents
  • Drug Combinations
  • Amoxicillin
  • Cloxacillin