Abstract
Rh2(S-nap)4, a chiral dirhodium tetracarboxamidate complex, has been developed and shown to be an effective catalyst for the asymmetric, intramolecular C-H amination of sulfamate esters. Enantiomeric excesses range from 60-99% for a collection of disparately substituted 3-arylpropylsulfamates. In addition, Rh2(S-nap)4 is found to promote chemoselective allylic C-H oxidation of unsaturated sulfamates, a property not observed with other dirhodium complexes tested to date.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Allyl Compounds / chemistry
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Amides / chemistry
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Amination
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Amines / chemical synthesis*
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Amines / chemistry
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Benzene Derivatives / chemistry
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Carboxylic Acids / chemical synthesis
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Catalysis
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Esters / chemistry
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Organometallic Compounds / chemistry
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Rhodium / chemistry*
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Stereoisomerism
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Sulfonic Acids / chemistry
Substances
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Allyl Compounds
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Amides
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Amines
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Benzene Derivatives
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Carboxylic Acids
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Esters
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Organometallic Compounds
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Sulfonic Acids
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sulfamic acid
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Rhodium