Oscillations in a patchy environment disease model

Math Biosci. 2008 Sep;215(1):1-10. doi: 10.1016/j.mbs.2008.05.001. Epub 2008 May 16.

Abstract

For a single patch SIRS model with a period of immunity of fixed length, recruitment-death demographics, disease related deaths and mass action incidence, the basic reproduction number R(0) is identified. It is shown that the disease-free equilibrium is globally asymptotically stable if R(0)<1. For R(0)>1, local stability of the endemic equilibrium and Hopf bifurcation analysis about this equilibrium are carried out. Moreover, a practical numerical approach to locate the bifurcation values for a characteristic equation with delay-dependent coefficients is provided. For a two patch SIRS model with travel, it is shown that there are several threshold quantities determining its dynamic behavior and that travel can reduce oscillations in both patches; travel may enhance oscillations in both patches; or travel can switch oscillations from one patch to another.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Outbreaks / statistics & numerical data
  • Disease Transmission, Infectious / statistics & numerical data
  • Disease*
  • Humans
  • Mathematics
  • Models, Biological*
  • Travel