A refillable microfabricated drug delivery device for treatment of ocular diseases

Lab Chip. 2008 Jul;8(7):1027-30. doi: 10.1039/b804690e. Epub 2008 May 29.

Abstract

An implantable manually-actuated microfabricated drug delivery device was demonstrated as a new approach for delivering therapeutic compounds to ocular tissue in acute in vitro, ex vivo, and in vivo studies.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Dimethylpolysiloxanes / chemistry
  • Drug Delivery Systems / instrumentation*
  • Equipment Reuse
  • Eye / pathology*
  • Eye Diseases / drug therapy*
  • Eye Diseases / pathology
  • Feasibility Studies
  • Humans
  • Needles

Substances

  • Dimethylpolysiloxanes