Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: are erm(A) pneumococcal isolates overlooked?

Scand J Infect Dis. 2008;40(6-7):584-7. doi: 10.1080/00365540701854717.

Abstract

Erm(A) is rarely reported as erythromycin resistance determinant in pneumococci. One invasive erm(A) isolate was initially tested intermediate erythromycin resistant using E-test. However, upon re-testing it was resistant, thus close to the breakpoint value. This may be a reason why erm(A) only rarely is reported to cause resistance in pneumococci.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Drug Resistance, Bacterial*
  • Erythromycin / pharmacology*
  • Humans
  • Male
  • Methyltransferases / genetics*
  • Microbial Sensitivity Tests
  • Middle Aged
  • Pneumococcal Infections / microbiology*
  • Streptococcus pneumoniae / drug effects*
  • Streptococcus pneumoniae / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Erythromycin
  • Methyltransferases
  • ErmA protein, Bacteria