Abstract
The uniform use in Canada of a single Haemophilus influenzae type b conjugate vaccine in combination with diphtheria, tetanus, acellular pertussis, and inactivated poliovirus vaccines (DTaP.IPV/Hib) facilitates ongoing assessment of vaccine effectiveness, including any effects of recently added concurrent vaccinations and increasing time since vaccination. Surveillance at 12 pediatric centers in 2004-2007 indicates that vaccine failures remain rare and case totals approach an irreducible minimum, with no age shift.
MeSH terms
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Adolescent
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Bacterial Capsules / administration & dosage*
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Bacterial Capsules / immunology
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Canada / epidemiology
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Child
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Child, Preschool
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Diphtheria-Tetanus-acellular Pertussis Vaccines / administration & dosage*
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Diphtheria-Tetanus-acellular Pertussis Vaccines / immunology
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Haemophilus Infections / epidemiology
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Haemophilus Infections / prevention & control*
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Haemophilus Vaccines / administration & dosage*
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Haemophilus Vaccines / immunology
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Haemophilus influenzae type b / immunology*
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Humans
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Immunization Programs
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Incidence
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Infant
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Infant, Newborn
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Poliovirus Vaccine, Inactivated / administration & dosage*
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Poliovirus Vaccine, Inactivated / immunology
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Treatment Outcome
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Vaccines, Combined / administration & dosage*
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Vaccines, Combined / immunology
Substances
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Diphtheria-Tetanus-acellular Pertussis Vaccines
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Haemophilus Vaccines
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Haemophilus influenzae type b polysaccharide vaccine
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Poliovirus Vaccine, Inactivated
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Vaccines, Combined