Cyano-bridged coordination polymer nanoparticles with high nuclear relaxivity: toward new contrast agents for MRI

Dalton Trans. 2008 Jul 28:(28):3658-60. doi: 10.1039/b808221a. Epub 2008 May 29.

Abstract

New water-soluble paramagnetic Gd-containing cyano-bridged metallic coordination polymer nanoparticles with a chitosan shell show high nuclear relaxivity in acidic water which is up to six times higher than that of the actually used Gd-chelates.

MeSH terms

  • Contrast Media / chemistry*
  • Gadolinium / chemistry
  • Magnetic Resonance Imaging / methods*
  • Magnetics
  • Metal Nanoparticles / chemistry*
  • Nitriles / chemistry*
  • Polymers / chemistry*
  • Temperature
  • Water / chemistry

Substances

  • Contrast Media
  • Nitriles
  • Polymers
  • Water
  • Gadolinium