Modification of second cancer risk after malignant melanoma by parental history of cancer

H Zhang; J Lorenzo Bermejo; J Sundquist; K Hemminki

doi:10.1038/sj.bjc.6604489

Modification of second cancer risk after malignant melanoma by parental history of cancer

Br J Cancer. 2008 Aug 5;99(3):536-8. doi: 10.1038/sj.bjc.6604489. Epub 2008 Jul 15.

Authors

H Zhang¹, J Lorenzo Bermejo, J Sundquist, K Hemminki

Affiliation

¹ Division of Molecular Genetic Epidemiology, German Cancer Research Center, DKFZ, Heidelberg, Germany.

Abstract

The Swedish Family-Cancer Database was used to quantify the incidence of second tumours in melanoma patients with a parental history of cancer. Patients with parents affected by melanoma showed a 32.3-fold risk of second primary melanomas, which was greater than a multiplicative interaction.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Cohort Studies
Humans
Medical History Taking*
Melanoma / pathology*
Middle Aged
Neoplasms, Second Primary / epidemiology*
Parents
Retrospective Studies
Risk Factors
Skin Neoplasms / pathology*
Sweden / epidemiology