Mitigating risky sexual behaviors among Russian narcology hospital patients: the PREVENT (Partnership to Reduce the Epidemic Via Engagement in Narcology Treatment) randomized controlled trial

Addiction. 2008 Sep;103(9):1474-83. doi: 10.1111/j.1360-0443.2008.02251.x. Epub 2008 Jul 10.

Abstract

Aim: To assess the effectiveness of a sexual risk reduction intervention in the Russian narcology hospital setting.

Design, setting and participants: This was a randomized controlled trial from October 2004 to December 2005 among patients with alcohol and/or heroin dependence from two narcology hospitals in St Petersburg, Russia.

Intervention: Intervention subjects received two personalized sexual behavior counseling sessions plus three telephone booster sessions. Control subjects received usual addiction treatment, which did not include sexual behavior counseling. All received a research assessment and condoms at baseline.

Measurements: Primary outcomes were percentage of safe sex episodes (number of times condoms were used / by number of sexual episodes) and no unprotected sex (100% condom use or abstinence) during the previous 3 months, assessed at 6 months.

Findings: Intervention subjects reported higher median percentage of safe sex episodes (unadjusted median difference 12.7%; P = 0.01; adjusted median difference 23%, P = 0.07); a significant difference was not detected for the outcome no unprotected sex in the past 3 months [unadjusted odds ratio (OR) 1.6, 95% confidence interval (CI) 0.8-3.1; adjusted OR 1.5, 95% CI 0.7-3.3].

Conclusions: Among Russian substance-dependent individuals, sexual behavior counseling during addiction treatment should be considered as one potential component of efforts to decrease risky sexual behaviors in this HIV at-risk population.

Trial registration: ClinicalTrials.gov NCT00183118.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Condoms / statistics & numerical data
  • Female
  • Follow-Up Studies
  • HIV Infections / prevention & control*
  • Health Education
  • Humans
  • Male
  • Middle Aged
  • Risk Reduction Behavior*
  • Russia
  • Safe Sex
  • Sex Counseling*
  • Substance-Related Disorders / psychology*
  • Substance-Related Disorders / therapy
  • Unsafe Sex / prevention & control*

Associated data

  • ClinicalTrials.gov/NCT00183118