Abstract
Two new bromotyrosine alkaloids, purealidins T and U (1 and 2, resp.), along with five known bromotyrosines 3-7, were isolated from marine sponge Pseudoceratina sp. Their structures were elucidated on the basis of extensive spectroscopic data (CD, IR, 1D- and 2D-NMR, and MS) analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification*
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Animals
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Cell Line, Tumor / drug effects
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Circular Dichroism
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Humans
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Nuclear Magnetic Resonance, Biomolecular
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Porifera / chemistry
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Spectrometry, Mass, Electrospray Ionization
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Tandem Mass Spectrometry
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Tyrosine / analogs & derivatives*
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Tyrosine / isolation & purification
Substances
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Alkaloids
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bromotyrosine
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Tyrosine