Abstract
New methods to distinguish between nontypeable Haemophilus influenzae and nonhemolytic H. haemolyticus were compared. The results of iga variable region hybridization to dotblots and library-on-a-slide microarrays were more similar to a "gold standard" multigenephylogenetic tree than iga-conserved region hybridization or P6 7F3 epitope immunoblots.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
MeSH terms
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Bacterial Outer Membrane Proteins / chemistry
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Carrier State / microbiology*
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Child, Preschool
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Epitopes / analysis
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Haemophilus / classification*
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Haemophilus / genetics
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Haemophilus / isolation & purification
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Haemophilus Vaccines / chemistry
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Haemophilus influenzae / classification*
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Haemophilus influenzae / genetics
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Haemophilus influenzae / isolation & purification
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Humans
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Immunoblotting / methods*
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Nucleic Acid Hybridization / methods
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Oligonucleotide Array Sequence Analysis / methods*
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Pharynx / microbiology
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Phylogeny*
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Serine Endopeptidases / genetics*
Substances
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Bacterial Outer Membrane Proteins
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Epitopes
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Haemophilus Vaccines
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P6 outer membrane protein, Haemophilus
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Serine Endopeptidases
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IgA-specific serine endopeptidase