Abstract
We investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in China and determined the susceptibility of S. aureus to 26 antimicrobial agents, including ceftobiprole, linezolid, and tigecycline. A total of 798 isolates were collected and tested by agar dilution. The mean prevalence of MRSA was 50.4%, the highest in Shanghai (80.3%), followed by those in Beijing (55.5%) and Shenyang (50.0%). Only 4.2% to 12.6% of MRSA were susceptible to erythromycin, fluoroquinolones, gentamicin, and tetracycline. All isolates were susceptible to teicoplanin, vancomycin, linezolid, tigecycline, and ceftobiprole.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetamides / pharmacology*
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Anti-Bacterial Agents / pharmacology*
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Cephalosporins / pharmacology*
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China / epidemiology
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Humans
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Linezolid
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Methicillin / pharmacology
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Methicillin Resistance
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Microbial Sensitivity Tests
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Minocycline / analogs & derivatives*
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Minocycline / pharmacology
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Oxazolidinones / pharmacology*
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Prevalence
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / isolation & purification
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Tigecycline
Substances
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Acetamides
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Anti-Bacterial Agents
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Cephalosporins
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Oxazolidinones
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ceftobiprole
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Tigecycline
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Minocycline
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Linezolid
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Methicillin