Abstract
A gated synthetic ion channel with beta-cyclodextrin as the pore and azobenzene as the gate is reported. Irradiation converts a tethered trans-azobenzene to cis-azobenzene which likely transforms the channel from a self-inclusion complex to a dissociated structure. This transformation results in an increase in anion transport and a decrease in cation transport across a phospholipid vesicle membrane.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Azo Compounds / chemical synthesis
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Azo Compounds / chemistry*
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Ion Channel Gating / radiation effects
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Ion Channels / chemical synthesis
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Ion Channels / chemistry*
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Ion Channels / radiation effects
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Phospholipids / chemistry
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Photochemistry
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Ultraviolet Rays
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beta-Cyclodextrins / chemical synthesis
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beta-Cyclodextrins / chemistry*
Substances
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Azo Compounds
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Ion Channels
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Phospholipids
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beta-Cyclodextrins
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azobenzene