Abstract
Repeated stress led to antipodal directions in immune system and cytochrome P450 activities of normotensive and hypertensive rats. Enhancement of the Reaction of Delayed Hypersensitivity, suppression of cytochrome P450-mediated monooxigenase activities were observed in Wistar rats. On the contrary, in the NISAG decrease of the Reaction Delayed Hypersensitivity, elevation of cytochrome P450-mediated monooxigenase activities were observed, as comparison with Wistar rats.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Aryl Hydrocarbon Hydroxylases / immunology
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Aryl Hydrocarbon Hydroxylases / metabolism
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Cytochrome P-450 CYP1A1 / immunology
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Cytochrome P-450 CYP1A1 / metabolism
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Cytochrome P-450 CYP2B1 / immunology
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Cytochrome P-450 CYP2B1 / metabolism
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Hypersensitivity, Delayed / enzymology
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Hypersensitivity, Delayed / immunology*
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Hypertension / enzymology
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Hypertension / immunology*
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Mixed Function Oxygenases / immunology*
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Mixed Function Oxygenases / metabolism
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Rats
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Rats, Wistar
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Steroid Hydroxylases / immunology
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Steroid Hydroxylases / metabolism
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Stress, Physiological / enzymology
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Stress, Physiological / immunology*
Substances
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Mixed Function Oxygenases
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Steroid Hydroxylases
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Aryl Hydrocarbon Hydroxylases
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Cytochrome P-450 CYP1A1
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Cytochrome P-450 CYP2B1
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steroid 16-beta-hydroxylase