Myocardial contractile performance during acute coronary occlusion with special emphasis on nonoccluded regions

Acta Physiol Scand Suppl. 1991:599:99-107.

Abstract

Ischaemia of the left ventricle caused by coronary artery occlusion generally leads to less changes in overall ventricular performance than would be expected from the amount of ischaemic, noncontracting tissue. Ischaemic myocardium shows elongation of segment lengths and paradoxial movement during contraction of the left ventricle. Compensation for the loss of contractile tissue is most likely related to increased performance of the nonischaemic myocardium and the most likely mechanisms involved are discussed. The effect of increased preload, brought about by increased left ventricular end-diastolic pressure following coronary occlusion, on nonischaemic parts appear to be the most important mechanism of compensation.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological
  • Animals
  • Blood Pressure
  • Coronary Disease / physiopathology*
  • Heart Rate
  • Myocardial Contraction*
  • Myocardium / pathology*
  • Regional Blood Flow
  • Ventricular Function, Left*