[A cause of intracerebral calcifications that should be known: pseudohypoparathyroidism Ib]

Arch Pediatr. 2008 Sep;15(9):1433-6. doi: 10.1016/j.arcped.2008.06.016. Epub 2008 Aug 3.
[Article in French]

Abstract

In children, pseudohypoparathyroidism (PHP) is a rare but classical cause of basal ganglia calcifications. It is caused by resistance to parathormone (PTH). Hypocalcemia, which may be symptomatic, is its main feature. We report the case of a 13-year-old boy, affected by type Ib PHP revealed by hypocalcemia and seizures, with basal ganglia calcifications on the CT scan. We describe the characteristics of the 2 main types of PHP and emphasize the search for this disease when basal ganglia calcifications are discovered, even fortuitously, on a cerebral CT scan.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Basal Ganglia Diseases / diagnostic imaging
  • Basal Ganglia Diseases / etiology*
  • Calcinosis / diagnostic imaging
  • Calcinosis / etiology*
  • Humans
  • Hypocalcemia / etiology
  • Male
  • Pseudohypoparathyroidism / diagnosis*
  • Radiography
  • Seizures / etiology