Abstract
After many years of effort with only modest result, the last 5 years has seen a tremendous surge in our understanding of the genetics of diabetes. This review will focus on the therapeutic implications of diagnosing monogenic diabetes and the recent advances in type 1 and type 2 diabetes genetics following the development of Genome Wide Association studies.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Blood Glucose
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Diabetes Mellitus / drug therapy*
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Diabetes Mellitus / genetics*
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Genetic Predisposition to Disease / genetics*
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Hepatocyte Nuclear Factor 1-alpha / metabolism
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Humans
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Hypoglycemic Agents / therapeutic use*
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Potassium Channels, Inwardly Rectifying / metabolism
Substances
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Blood Glucose
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HNF1A protein, human
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Hepatocyte Nuclear Factor 1-alpha
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Hypoglycemic Agents
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Kir6.2 channel
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Potassium Channels, Inwardly Rectifying