Primary orbital malignant lymphoma: a clinicopathology study of 17 cases

Graefes Arch Clin Exp Ophthalmol. 1991;229(3):206-9. doi: 10.1007/BF00167868.

Abstract

We investigated the clinicopathologic characteristics of 17 patients (13 men and 4 women) with primary orbital malignant lymphoma using the Working Formulation. Most of the cases belonged to the low-grade malignancy group, and more women than men were in the histologically high-grade malignancy group. The phenotype of the tumor cells was investigated immunohistochemically. All cases showed the monoclonal feature of a B-cell lineage. All patients received chemotherapy with or without radiotherapy. Of 16 subjects, 15 achieved a complete remission; none of these patients has had a recurrence since the completion of the initial therapy (range of follow-up from 16 months to 10 years). One patient died.

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Conjunctival Neoplasms / drug therapy
  • Conjunctival Neoplasms / pathology*
  • Conjunctival Neoplasms / radiotherapy
  • Female
  • Follow-Up Studies
  • Humans
  • Immunophenotyping
  • Lymphoma, B-Cell / drug therapy
  • Lymphoma, B-Cell / pathology*
  • Lymphoma, B-Cell / radiotherapy
  • Lymphoma, Non-Hodgkin / drug therapy
  • Lymphoma, Non-Hodgkin / pathology*
  • Lymphoma, Non-Hodgkin / radiotherapy
  • Male
  • Middle Aged
  • Orbital Neoplasms / drug therapy
  • Orbital Neoplasms / pathology*
  • Orbital Neoplasms / radiotherapy
  • Sex Factors