Evaluation of nanosuspensions for absorption enhancement of poorly soluble drugs: in vitro transport studies across intestinal epithelial monolayers

AAPS J. 2008 Sep;10(3):435-8. doi: 10.1208/s12248-008-9050-7. Epub 2008 Aug 9.
No abstract available

MeSH terms

  • Budesonide / chemistry
  • Budesonide / metabolism
  • Caco-2 Cells
  • Cell Membrane Permeability / drug effects*
  • Chromatography, High Pressure Liquid
  • Humans
  • Intestinal Absorption / drug effects*
  • Nanoparticles / chemistry*
  • Particle Size
  • Pharmaceutical Preparations* / chemistry
  • Pharmaceutical Preparations* / metabolism
  • Solubility
  • Spironolactone / chemistry
  • Spironolactone / metabolism
  • Suspensions

Substances

  • Pharmaceutical Preparations
  • Suspensions
  • Spironolactone
  • Budesonide