This qualitative study examines the motivations of people who had a positive result as part of the colorectal cancer screening programme, and who did not follow-up with further recommended tests; whereas good medical practice requires the a colonoscopy subsequent to a positive Hemoccult test. Twelve semi-directed interviews were conducted. The quality of the doctor - patient relationship strongly influences the acceptance of having a colonoscopy. This data highlights the necessary capacity of the doctor to convey a rational message while also taking into account the emotional turmoil provoked by the uncertainty and worry linked to receiving a first positive result in a cancer screening test. Working with the medical profession to advocate for a systematic colonoscopy as an essential follow-up to a positive Hemoccult test is critical. For many of these doctors, doing the Hemoccult test is regarded as the screening standard, but in their view a subsequent colonoscopy is not currently a part of this norm. Recommendations are proposed, aiming to improve the acceptance of the organized screening by the population.